Sarcoidosis Answers for Physicians, Nurses and Patients

Here at SarcInfo, between 2002 and 2004, we identified the cause of Sarcoidosis, and successfully trialled a curative antimicrobial therapy. During 2005 and 2006 the US FDA designated the antibiotics Clindamycin and Minocycline as Orphan Products in the treatment of Sarcoidosis, and studies are ongoing elsewhere.

For information about this breakthrough, please post your questions at the current study-site, or the Autoimmunity Research Foundation.
 
This archive of the historic study is maintained by volunteers from the Foundation. The material here provides useful background, but much of it is now out-of-date.

** Patient Tutorials **

 Click here to read "WHY DID I GET SARCOIDOSIS? WHY ME? 

  Click here to read "REMISSION IN SARCOIDOSIS"  

 How a Pathologist can see Bacteria causing Sarcoidosis 

"How does Doctor measure my ACE, and my D-metabolites?"

 Weaning from Prednisone

 Protecting your eyes in Sarcoidosis

Vit.D and Calcium in Sarcoidosis

Hypervitaminosis D Symptoms    The SarcInfo F.A.Q.

Medical Abbreviations          CBC Radio Show

Protocol Phase 1-First 3 months

  

** Papers for Physicians **

Antibacterial Therapy induces Remission 

Implications for Autoimmune Disease 
(Here is Fulltext preprint)

Antibacterial mechanisms for ARBs 

Antibiotics in Sarcoidosis- The 1st Year 

Rationale for abx in Sarcoidosis 

1,25-D and Angiotensin II

"New Treatments Emerge.."

Jarisch-Herxheimer in Sarcoidosis

Vit.D and Calcium in Sarcoidosis

Protocol Phase 1-First 3 months

The NIH ACCESS Study finds Sarcoidosis does not go away - Click here to see, and print, the brochure


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 Gallium Scan--Yes or No
Author: Caroline (---.win.org)
Date:   05-14-02 21:08

Hi all,
I run across a lot of reading that mentions having a Gallium Scan. I asked my PCP and Neuro and neither think it necessary since it would not change my treatment at this point.

Anyone have strong feelings Pro or Con and why?

Caroline
 
 Re: Gallium Scan--Yes or No
Author: Admin (---.cu27.vnnyca.adelphia.net)
Date:   05-15-02 07:14

A gallium scan is intended to locate areas of infection and inflammation within the body

After I.V. injection of a radio-active compound, the patient is scanned at varying intervals up to 96 hours after the injection. Inflammed tissues, such as lymphoma (cancer) or infection or sarcoid, can be seen, and sometimes distinguished, on the Xray, CAT or PET scanners used to detect (scan) the emitted radiation.

There are many limitations with a "Gallium Scan'. The procedure is costly, it requires 48 to 72 hours for proper interpretation, and the uptake reverses quickly during corticosteroid therapy. New radionucleides have been used to try and overcome these limitations, with varying success.

The use of a more sensitive P.E.T. scanner can often assist in obtaining contrast, especially with weaker radionucleides and at greater times after the initial injection.

If your doctor can't figure out the presence and location of inflammation from Xrays, CAT or MRI scans then a gallium scan usually ordered. But it can be an imprecise test, and other scanning technologies are more suitable to follow the progress of the inflammation.

..Trevor..
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Historical perspective on Sarcoidosis:


  1. The John's Hopkins Vasculitis Center: Prednisone Side Effects (incl. PHOTOS and PHOTOGRAPHS)
  2. Steroid-Treated patients Have higher risk of Cardiac problems
  3. "Evidence Growing That Inhaled Steroids, Like Steroid Pills, Can Cause Bone Loss"
  4. "Corticosteroids contribute to the prolongation of the disease by delaying resolution"
  5. "No data to suggest that corticosteroid therapy alters long-term disease progression"
  6. Cochrane Review - "Oral and Inhaled Corticosteroids have no discernible effect on lung function"
  7. Prednisone Improves Symptoms but not Lung Function in Sarcodiosis
  8. There is no conclusive evidence that corticosteroids affect the development of irreversible pulmonary damage
  9. Clinical Guideline For Treatment Of Arthritis Pain
  10. Angiotensin II receptor on BALF macrophages from Japanese patients with active sarcoidosis

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